Glade vs Hand code

[NewbieNoob <optomatic rogers com>]

Hi There
I rebuild and resell instruments used in laboratories. I am presently trying
to build an open source PyGtk  application to communicate and process data
from these instruments. I am hoping to charge a small fee for the
application from which I could then use to pay more talented people to
improve its quality.

So my question is:
If I want other people to be able to contribute code to my application is it
better to have the application built with the help of Glade or should I hand
code the application?

I am just trying to build a firm foundation through hand-coding right now
but Glade seems to be everywhere. I am not sure if anyone hand codes medium
sized applications, would it be crazy to do so?

Thanks for your time-Patrick 
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